Biomolecules Folding and Disease
The course Laboratory of Bioinformatics 1 (66563) includes in the second semester a 60-hours module given by
The course director is Prof. Rita Casadio.
The module is running from March 13 to May 3, 2018 in the Laboratory of Bioinformatics at the ground floor of Via San Giacomo 9/2 (back entrance).
This page will include all the slides and materials of the lectures.
|Introduction and Basic Concepts||March 13, 2018.|
|Protein and RNA Structure Alignment||March 15 and 16, 2018.|
|Multiple Alignments||March 20 and 22, 2018.|
|Hidden Markov Models||March 23, 2018.|
|HMM Alignments||March 27, 2018.|
|HMMER||March 28, 2018.|
|Introduction to the Project||April 5 and 6, 2018.|
|Project Implementation||April 10-24, 2018.|
|Protein Structure Prediction||April 26 and 27, 2018.|
|Protein Structure Analysis and Variants||May 3, 2018.|
|This is a theoretical and hands-on module which requires the use of PC. Students need to use their own laptop. Practical session of the course will be performed on a Linux OS.|
Structural Bioinformatics II Edition:
Structural Comparison and Alignment.
by Marti-Renom et al.
A Comprehensive Benchmark Study of Multiple Sequence Alignment Methods: Current Challenges and
Future Perspectives. PLOS ONE, 2011.
by Thompson et al.
Pfam: the protein families database.
Nucleic Acids Research, 2014.
by Finn et al.
Assignment of protein sequences to existing domain and family classification systems: Pfam and the PDB.
by Xu and Dunbrack.
In this page we included the
evaluation form anonymously compiled by the
participants to evaluate the quality of our course. Answers submitted with
numbers from 1 (No) to 4 (Yes) have been included in the following statistics
calculated by R. The evaluation form was compiled by 14 participants which rated
the course with an average score of 3.3 over 4.
The received positive and negative comments will be published soon.
|March 2017:||The previous edition of the Module 2 of the Laboratory of Bioinformatics 1 course (14 March - 4 May, 2017) was successfully completed (more information are available here).|