Biomolecules Folding and Disease |
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The course Laboratory of Bioinformatics 1 (66563)
includes in the second semester a 58-hour module given by
Emidio Capriotti.
The course director is Prof. Rita Casadio.
The module was running from March 8 to April 26, 2022 and the lectures will be given in presence and online through the
URL http://bit.do/lb1-lectures.
To record your presence during the lectures, please fill the following form.
This page will include all the slides and materials of the course.
Course Schedule | |
Introduction and Basic Concepts | 8 March, 2022. |
Protein and RNA Structure Alignment | 10 and 11 March, 2022. |
Multiple Alignments | 15, 17 and 18 March, 2022. |
Probabilistic Models for Biological Sequences | 22 March, 2022. |
Hidden Markov Models | 25 and 29 March, 2022. |
HMM for Seqnence Alignment | 31 March, 2022. |
HMMER | 1 April, 2022. |
Introduction to the Project | 5, 7 and 8 April, 2022. |
Project Implementation | 12-22 April, 2022. |
Hands-On Programming Sessions |
This is a theoretical and hands-on module which requires the use of PC. Students need to use their own laptop. Practical session of the course will be performed on a Linux OS. |
Marti-Renom et al.
Structural Bioinformatics II Edition:
Structural Comparison and Alignment.
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Thompson et al.
A Comprehensive Benchmark Study of Multiple Sequence Alignment Methods: Current Challenges and
Future Perspectives. PLOS ONE, 2011. |
El-Gebali et al.
The Pfam protein families database in 2019.
Nucleic Acids Research, 2019. |
Loewenstein et al.
Protein function annotation by homology-based inference.
Genome Biology, 2009. |
Xu and Dunbrack.
Assignment of protein sequences to existing domain and family classification systems: Pfam and the PDB.
Bioinformatics, 2012. |
March 2021: | The previous edition of the Module 2 of the Laboratory of Bioinformatics 1 course (9 March - 30 April, 2021) was successfully completed (more information are available here). |
March 2020: | The previous edition of the Module 2 of the Laboratory of Bioinformatics 1 course (10 March - 30 April, 2020) was successfully completed (more information are available here). |
March 2019: | The previous edition of the Module 2 of the Laboratory of Bioinformatics 1 course (12 March - 17 April, 2019) was successfully completed (more information are available here). |
March 2018: | The previous edition of the Module 2 of the Laboratory of Bioinformatics 1 course (13 March - 3 May, 2018) was successfully completed (more information are available here). |
March 2017: | The previous edition of the Module 2 of the Laboratory of Bioinformatics 1 course (13 March - 4 May, 2017) was successfully completed (more information are available here). |